Scientists race to test vaccines for Uganda’s Ebola outbreak
A multipronged international effort has begun to pull out all the stops to launch trials of experimental Ebola vaccines in Uganda, which declared an outbreak of the deadly disease on 20 September. According to the most recent World Health Organization (WHO) update, Uganda has had 18 confirmed and 18 suspected cases of Ebola, including 23 deaths—an unusually high case fatality rate of 64%. A trial of a vaccine candidate that’s farthest along in development could launch before the end of next month.
Proven vaccines exist for Zaire ebolavirus, which has led to a dozen outbreaks in the neighboring Democratic Republic of the Congo (DRC) and was responsible for the massive Ebola epidemic in West Africa in 2014. But those vaccines cannot control this outbreak because it’s being driven by a dis...









